Suicidal Ideation Common in Women Seeking Treatment for Premenstrual Dysphoric Disorder

In our clinic, we see a lot of women who existing with suicidal ideation emerging or worsening throughout the premenstrual section of the menstrual cycle.  Though previous reports have documented an association among Premenstrual Dysphoric Problem (PMDD) and suicidal ideation, most of these scientific tests have not verified the prognosis using potential rankings and DSM diagnostic standards.  A modern review from Wikman and colleagues assesses the prevalence of suicidal ideation in females with PMDD confirmed employing much more stringent standards..

In this analyze, the members ended up 110 gals recruited to participate in a randomized placebo-managed scientific demo for the procedure of PMDD concerning January 15, 2017 and Oct 19, 2019. The diagnosis of PMDD was confirmed utilizing possible day-to-day rankings in line with DSM-5 conditions. Current suicidal ideation was calculated utilizing the MADRS-S administered through the late luteal phase of the menstrual cycle.  

Suicidal ideation was noted in the course of the late luteal period by virtually 40% of the girls with confirmed PMDD (n = 43, 39.1%).  Latest suicidal ideation was additional frequent in females reporting preceding psychological remedy for PMDD (OR 5.63, 95% CI 1.07-29.49).  In addition, higher depressive indicators throughout the late luteal stage have been linked with suicidal ideation  (OR 1.17, 95% CI 1.10-1.25).  In contrast, better rankings of self-rated health and fitness had been involved with decreased odds ratios for present suicidal ideation (OR .98, 95% CI .96-.99).

In this inhabitants looking for procedure for PMDD, suicidal ideation is really prevalent, impacting about 40% of the females.  This examine is distinctive from prior research analyzing the affiliation in between PMDD and suicidal ideation in the latest review, the diagnosis of PMDD was verified prospectively in accordance to DSM diagnostic criteria and suicidal ideation was measured concurrently.  Though the review does not evaluate suicidal ideation in a neighborhood sample of women of all ages with PMDD, the conclusions of this review suggest that suicidal ideation is frequent amongst girls trying to get procedure for PMDD.  

Ruta Nonacs, MD PhD

Wikman A, Sacher J, Bixo M, Hirschberg AL, Kopp Kallner H, Epperson CN, Comasco E, Sundström Poromaa I. Prevalence and correlates of current suicidal ideation in females with premenstrual dysphoric problem. BMC Womens Well being. 2022 Feb 1122(1):35.

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